
Discover the Power of Nutrients

5 o’clock™ provides 100% of the Daily Values (DV) of all B vitamins and zinc to replenish some vitamins depleted by alcohol consumption, plus silymarin (Milk Thistle) and NAC (N-acetyl cysteine) to support and help detoxify the liver*.
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
It is important to note that while these nutrients can provide support, they should not be viewed as a remedy for excessive drinking or a substitute for responsible alcohol consumption. Maintaining a balanced diet, staying hydrated, and drinking in moderation are essential for overall health. As always, consult a healthcare professional before making changes to your supplement regimen, especially if you have underlying health conditions or concerns.
* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Metabolizing alcohol requires nutrients. When these nutrients (vitamins) are used to break down alcohol instead of aiding the body’s cells, certain body functions can become hindered. Many of the vitamins that are utilized to break down alcohol are essential to physical and emotional health. Depression is the most common emotional symptom due to regular alcohol use and may be due to deficiencies in the vitamins utilized to metabolize alcohol. Most of these B vitamins are water soluble and can’t be stored in our bodies, so they need to be replaced regularly.
US surgeon general Vivek Murthy, MD, issued an advisory, calling for alcoholic beverages to carry a warning label about cancer risk. The advisory flagged alcohol as the third leading preventable cause of cancer in the United States, after tobacco and obesity, and highlighted people’s limited awareness about the relationship between alcohol and cancer risk.

B vitamins, which can be depleted with regular alcohol use, are essential for energy because they help the body use fats, proteins, and carbohydrates. They are also needed for brain function, nervous system health, cell division, red blood cell formation, healthy skin, hair, eyes and liver, wound healing, and a healthy immune system.
Zinc, a mineral that is essential to the production of energy, is also depleted with regular alcohol use.
Cofactor for ADH: Zinc is a vital cofactor for alcohol dehydrogenase (ADH), the primary enzyme responsible for metabolizing ethanol in the liver.
No Direct Breakdown: Zinc does not directly break down alcohol itself; its role is to enable the enzymatic process.
Alcohol Causes Zinc Deficiency: Chronic alcohol intake can deplete the body’s zinc levels by reducing absorption and increasing excretion.
Deficiency Slows Metabolism: A lack of zinc can impair ADH function, slowing alcohol metabolism and prolonging exposure to toxic byproducts like acetaldehyde.
Protective Effects: Adequate zinc levels or supplementation can help reduce oxidative stress, protect the liver, and potentially lessen hangover severity.
Not a Cure for Overconsumption: Zinc supplementation should not be seen as a way to counteract excessive drinking, but rather as a means of supporting overall health and metabolic function.
Silymarin is derived from the seeds and fruit from the milk thistle plant, Silybum marianum. It can help protect liver cells from damage and may help repair the liver. It is a safe and effective treatment option for a variety of liver diseases.
N-acetyl cysteine (NAC) is a supplement form of cysteine, a conditionally essential amino acid. NAC has many health benefits, including replenishing antioxidants and nourishing your brain. It also helps to detoxify your body to prevent or diminish liver and kidney damage.